Braun Lab

C. J. Braun*, A. C. Adames, D. Saur & R. Rad*. Tutorial: design and execution of CRISPR in vivo screens. *Co-corresponding

Nature protocols (2022)
Journal Impact Factor₂₀₂₁: 17.021     

T. Kaltenbacher, J. Loprich, R. Maresch, J. Weber, S. Muller, R. Oellinger, N. Gross, J. Griger, N. de Andrade Kratzig, P. Avramopoulos, D. Ramanujam, S. Brummer, S. A. Widholz, S. Barthel, C. Falcomata, A. Pfaus, A. Alnatsha, J. Mayerle, M. Schmidt-Supprian, M. Reichert, G. Schneider, U. Ehmer, C. J. Braun, D. Saur, S. Engelhardt, and R. Rad. CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver.

Nature protocols (2022)
Journal Impact Factor₂₀₂₁: 17.021

J. Weber, C. J. Braun, D. Saur, R. Rad. In vivo functional screening for systems-level integrative cancer genomics. In vivo functional screening for systems-level integrative cancer genomics.

Nature Reviews Cancer (2020)
Journal Impact Factor₂₀₂₁: 69.800

M. Becker, H. Noll-Puchta, D. Amend, F. Nolte, C. Fuchs, I. Jeremias*, C. J. Braun*. CLUE: a bioinformatic and wet-lab pipeline for multiplexed cloning of custom sgRNA libraries.

Nucleic Acids Research (2020)
Journal Impact Factor₂₀₂₁: 19.160

C. J. Braun*, M. Stanciu*, P. L. Boutz*, J. C. Patterson, D. Calligaris, F. Higuchi, R. Neupane, S. Fenoglio, D. P. Cahill, H. Wakimoto, N. Y. R. Agar, M. B. Yaffe, P. A. Sharp, M. T. Hemann, J. A. Lees. Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma. *equal contributions

Cancer Cell (2017)

Journal Impact Factor₂₀₂₁: 38.585

C. J. Braun*, P. M. Bruno*, M. A. Horlbeck, L. A. Gilbert, J. S. Weissman, M. T. Hemann. Versatile in vivo regulation of tumor phenotypes by dCas9 mediated transcriptional perturbation. *equal contributions

PNAS (2016)

Journal Impact Factor₂₀₂₁: 10.700

I. G. Cannell, K. A. Merrick*, S. Morandell*, C. Z. Zhu, C. J. Braun, R. A. Grant, E. R. Cameron, M. Tsao, M.T. Hemann and M. B. Yaffe. A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-defective Tumors to Chemotherapy.

Cancer Cell (2015)

Journal Impact Factor₂₀₂₁: 38.585

C. J. Braun*, K. Boztug*, A. Paruzynski*, M. Witzel*, A. Schwarzer, M. Rothe, U. Modlich, R. Beier, G. Göhring, D. Steinemann, R. Fronza, C. R. Ball, R. Haemmerle, S. Naundorf, K. Kühlcke, M. Rose, C. Fraser, L. Mathias, R. Ferrari, M. R. Abboud, W. Al-Herz, I. Kondratenko, L. Maródi, H. Glimm, B. Schlegelberger, A. Schambach, M. H. Albert, M. Schmidt, C. von Kalle, and C. Klein. Gene Therapy for Wiskott-Aldrich Syndrome--long-term efficacy and genotoxicity. *equal contributions

Science translational medicine (2014)

Journal Impact Factor₂₀₂₁: 19.359

C. P. Pallasch, I. Leskov, C. J. Braun, D. Vorholt, A. Drake, Y. M. Soto-Feliciano, E. H. Bent, J. Schwamb, B. Iliopoulou, N. Kutsch, N. van Rooijen, L. P. Frenzel, C. M. Wendtner, L. Heukamp, K. A. Kreuzer, M. Hallek, J. Chen, and M. T. Hemann. Sensitizing Protective Tumor Microenvironments to Antibody-Mediated Therapy.

Cell (2014)

Journal Impact Factor₂₀₂₁: 66.850

Dorothea, Christian, Heidi & Federica having fun at our Christmas party

Dorothea presenting about dCas9 and transcriptional road blocks at Kubus Science Fair