Binder Lab

Forschungsgebiet
- Protective leukemia-niche interactions
- Immune evasion of leukemia via macrophages
- Liquid biopsy for high-risk leukemia
- Zebrafish xenograft model
Mehr Informationen zu unserer Forschung finden Sie auf unserer englischen Website.




Selected publications
The genotype of the original Wiskott phenotype. Binder V, Albert MH, Kabus M, Bertone M, Meindl A, and Belohradsky BH (2006). N Engl J Med 355, 1790-1793.
Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53. Gefen N*, Binder V*, Zaliova M, Linka Y, Morrow M, Novosel A, Edry L, Hertzberg L, Shomron N, Williams O, Trka J, Borkhardt A, and Izraeli S (2010). Leukemia 24, 89-96. * Both authors contributed equally to this work
High throughput in vivo phenotyping: The zebrafish as tool for drug discovery for hematopoietic stem cells and cancer. Binder V, and Zon LI (2012). Drug Discovery Today: Disease Models.
A new workflow for whole-genome sequencing of single human cells. Binder V*, Bartenhagen C*, Okpanyi V, Gombert M, Moehlendick B, Behrens B, Klein HU, Rieder H, Ida Krell PF, Dugas M, Stoecklein NH, and Borkhardt A (2014). Hum Mutat 35, 1260-1270. * Both authors contributed equally to this work
Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Li P*, Lahvic JL*, Binder V*, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC, and Zon LI (2015). Nature 523, 468-471.* These authors contributed equally to this work
Binder Lab
Kubus Research Building
Lindwurmstr. 2a
80337 München, Deutschland
vera.binder@med.uni-muenchen.de
Zebrafish Facility @ DZNE Munich, Feodor-Lynen-Str. 17, 81377 München, Deutschland