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                                                              1. CCRC-HaunerEN
                                                              2. Research Labs
                                                              3. Koletzko Lab

                                                              Koletzko Lab

                                                              • Subgroups

                                                                • Child and Family Health Academy (ChiFHA)
                                                                • Child Health Foundation (CHF)
                                                                • MS-Core Facility
                                                                • Clinical Study

                                                                Prof. Dr. med. Berthold Koletzko

                                                                ✉ Berthold.Koletzko@med.uni-muenchen.de

                                                                ☎ +49-89-4400-52826

                                                              • Four subgroups of Prof. Koletzko consist of Child and Familiy Health Academy (ChiFHA), Child Health Foundation, MS-Core Facility and Clinical Study.

                                                                Child and Family Health Academy (ChiFHA)

                                                                Child and Family Health Academy imparts high-quality, up-to-date, evidence-based education and training covering a wide range of health-related topics focusing focusing on the well-being of children and families. Our target audience is healthcare professionals, researchers, and new investigators around the world, who are aiming to improve healthcare services whilst fostering their careers through Continuing Medical Education (CME) & Continuing Professional Development (CPD).

                                                                ChiFHA’s vision is to be a worldwide-recognized benchmark Academy in the area of child and family health. Through accessible online and blended learning formats, we break cost, time and space barriers, for maximum outreach. Our end-goal is to support and improve worldwide health from early life stages through capacity building and empowerment of international healthcare professionals and researchers. Through global and regional academies and programmes, learners can select their course based on their topics of interest and specific content tailored to the requirements of each region.

                                                                The global programmes comprise projects ENeA Global, MOOC, Early Nutrition Specialist (ENS); while the regional programmes comprise projects EU funded projects ImpENSA and ENeA SEA, EATS Indonesia, EndObesity, ENeA Hebammenwissen, and Intereg CD Skills.

                                                                More information about ChiFHA at https://chifha.org

                                                                Child Health Foundation

                                                                The Child Health Foundation (CHF) is actively involved in the healthy development of children and adolescents. It informs the public on key health issues and, in collaboration with partners and specialists, explains preventive strategies that can be implemented in day care, kindergartens and schools.

                                                                The operative implementation of the foundation’s work is based on three pillars:

                                                                • Prevention with programs applicable in practice

                                                                • Competence in the field of health prevention

                                                                • Effective public education

                                                                Health promotion and prevention are especially important for children. Nowadays pediatric and adolescent medicine can successfully treat a broad variety of illnesses. Yet, health promotion and the prophylaxis of illnesses still have a long way to go and remain key priorities. Overall, the main goal of the CHF is to ensure the best possible start in life for children.

                                                                More information about the Child Health Foundation at https://www.kindergesundheit.de/

                                                                MS-Core Facility

                                                                The MS-Core Facility in the Dr. von Hauner Children´s Hospital performs targeted LC-MS/MS based analysis of biological samples such as plasma, serum, milk and tissue from humans as well as animals from small research studies (e.g. elephant milk, cat plasma and mouse tissue) to medium and large clinical cohort studies (e.g. HOPE, RisCoin, CORKUM, ToMi and CHOP). The MS-Core Facility team works in close collaboration with in-house LMU-Klinikum research groups as well as research groups from other international universities and companies to facilitate correct sample collection, processing, storage and shipment. Hence, we offer and provide support already during the planning and writing stage of a clinical study, which includes stablishing a suitable budget plan as well as setting up material transfer agreements. In addition, we also offer help and assistance for statistical data evaluation of LC-MS generated metabolome and lipidome data sets.

                                                                Our metabolomics platform analysis includes amino acids (20 proteinogenic AAs plus Cit and Orn), organic acids and keto-acids from the TCA-cycle (15), acyl-carnitins (60) and glycerophosphocholines (PCaa, PCae, LPCa, LPCe and SM; a = acyl and e = ether; 320). Besides that, we also perform method development for sample preparation and quantitative analysis of free short, medium and long chain fatty acids, endocannabinoids, bile acids and lipid hydrolysis, among others. Presently we are also establishing the Biocrates MxP Quant 500XL Kit in our lab. For further information, please visit our webpage:

                                                                https://www.ccrc-hauner.de/technology-platforms/mass-spectrometry/d990e77de89f6bfb

                                                                Clinical Study

                                                                The clinical study team performs clinical studies in the area of early nutrition, particularly, nutrition during the first 1000 days of life (conception until second year) and its long-term health consequences. Currently, several studies are ongoing:

                                                                - CHOP-study (Childhood Obesity project study): This is a clinical trial examining the effect of different protein intake during the first year of life on BMI in five European countries. Additionally, a breastfed observational group was observed. Currently, the follow-up with 19 to 20 years old adults is performed.

                                                                - GIRAFFE-study (Goat infant formula feeding and eczema study): This clinical trial aims to examine the effect goat formula compared to cow formula and its risk of developing atopic dermatitis and other allergic diseases during the first year of life. More information to this trial: Giraffe Study – Goat Infant Formula Feeding and Eczema study (giraffe-study.com)

                                                                - HOPE-study: This is an observational study examining the composition of breastmilk and its influential factors after birth and during the first and fourth month of life. More information can be found: HOPE-Studie | LMU Klinikum (lmu-klinikum.de)

                                                                - ToMI-study (Toddler milk intervention trial): The ToMI-study investigating the effect of protein intake during the second year of life on growth, development and metabolism. Currently, the follow-up with six years is performed. Further information: Tomi Studie | LMU Klinikum (lmu-klinikum.de)

                                                                - ProtEUs-study (Protein study): The aim of the ProtEUs-study was to examine the aminoacid composition during the first year of life on growth and development in children. This clinical trial is completed.

                                                                Besides performing clinical studies, the study group participate in several international projects, which aims to strengthen evidence . Current and former projects, we participate/participated are:

                                                                - BiomarKid: This project EU funded and is characterizing biomarkers of dietary patterns, physical activity and sleep in children and adolescents. More information: Research Framework (healthydietforhealthylife.eu)

                                                                - EndObesity: This project is developing strategies to prevent overweight and obesity during the first 1000 days of life. The project include stakeholder from different areas including research, interest groups, consumer and politics. Further reading: EndObesity - Strategien zur Verhinderung von Übergewicht und Adipositas bei Kindern in den ersten 1000 Lebenstagen (gesundheitsforschung-bmbf.de)

                                                                - LifeCycle: This project is completed. The overall aim of this project was to investigate the role of early-life stressors influencing health using a combined network of European cohorts focusing on pregnancy and childhood. More information: Home - LifeCycle (lifecycle-project.eu)

                                                              • Child and Family Health Academy (ChiFHA) Team

                                                                Dr. Shweta Feher

                                                                Associate Director ChiFHA

                                                                Scientific director: ENS & ENeA Hebammenwissen; Programme Head: EATS Indonesia, MOOC, ENeA Global; Programme Coordinator: ImpENSA, CD Skills, ENeA SEA

                                                                ✉ shweta.feher@med.uni-muenchen.de

                                                                ☎ 089- 4400- 52816

                                                                Rungrawee Loipimai

                                                                ChiFHA Communications Manager

                                                                Project Manager ImpENSA & ENeA SEA

                                                                ✉ rungrawee.loipimai@med.uni-muenchen.de

                                                                ☎ 089- 4400- 52832


                                                                Marina Sanchez

                                                                ChiFHA Scientific Content Manager

                                                                Project Manager, EATS INA

                                                                ✉ marina.sanchez@med.uni-muenchen.de

                                                                ☎ 089- 4400- 53104



                                                                Tania Duque

                                                                Scientific Content Developer & Reviewer

                                                                ✉ tania.duque@med.uni-muenchen.de

                                                                ☎ 089- 4400- 54165



                                                                Nina Bodenstab

                                                                Student Co-worker & Technical Support

                                                                ✉ nina.bodenstab@med.uni-muenchen.de


                                                                Martina Forro

                                                                ChiFHA Administration

                                                                Admin. Project Manager, CD Skills & EATS INA

                                                                ✉ martina.forro@med.uni-muenchen.de

                                                                ☎ 089- 4400- 57929


                                                                Erin Baudendistel-Happ

                                                                ChiFHA Technical Manager

                                                                Programme Manager, ENS

                                                                ✉ erin.baudendistelhapp@med.uni-muenchen.de

                                                                ☎ 089- 4400- 57896


                                                                Jelica Gencel

                                                                Scientific Content Developer & Reviewer

                                                                Project Manager, ENeA Global, MOOC & EndObesity

                                                                ✉ jelica.gencel@med.uni-muenchen.de

                                                                ☎ 089- 4400- 52981



                                                                Alexandra Hett

                                                                Programme Manager ENeA Hebammenwissen

                                                                ✉ alexandra.hett@med.uni-muenchen.de


                                                                Clinical Study Team


                                                                Dr. Veit Grote

                                                                Senior Epidemiologist, Pediatrician

                                                                ✉ veit.grote@med.uni-muenchen.de


                                                                Uschi Handel

                                                                Research associate

                                                                ✉ uschi.handel@med.uni-muenchen.de




                                                                Vanessa Jäger

                                                                Research associate

                                                                ✉ vanessa.jaeger@med.uni-muenchen.de




                                                                Johanna Ruf

                                                                Research associate, PHD student

                                                                ✉ johanna.ruf@med.uni-muenchen.de




                                                                Martina Totzauer

                                                                Research associate

                                                                ✉ martina.totzauer@med.uni-muenchen.de



                                                                Kristine Uhl

                                                                Study nurse

                                                                ✉ kristine.uhl@med.uni-muenchen.de



                                                                Tanja Nenning

                                                                Study nurse

                                                                ✉ tanja.nenning@med.uni-muenchen.de



                                                                Dr. Hans Demmelmair

                                                                Research associate

                                                                ✉ hans.demmelmair@med.uni-muenchen.de



                                                                Kathrin Gürlich

                                                                Research associate

                                                                ✉ kathrin.guerlich@med.uni-muenchen.de




                                                                Jill Ferry

                                                                Research associate, PHD student

                                                                ✉ jill.ferry@med.uni-muenchen.de




                                                                Angkasa Dudung

                                                                PHD student

                                                                ✉ angkasa.dudung@med.uni-muenchen.de




                                                                Nadja Antl

                                                                Research associate

                                                                ✉



                                                                Christiane Haesner-Stricker

                                                                Study nurse

                                                                ✉


                                                                MS-Core Facility Team

                                                                Dr. Jeannie Horak

                                                                Laboratory Head of the MS-Core Facility

                                                                ✉ Jeannie.Horak@med.uni-muenchen.de 

                                                                ☎ 089- 4400- 57971

                                                                Room: D1.05

                                                                Dr. Nilay Can

                                                                Biostatistician and Bioinformatician of the MS-Core Facility

                                                                ✉ Nilay.Can@med.uni-muenchen.de

                                                                ☎ 089- 4400- 53153

                                                                Room: D1.05


                                                                Yuntao Hao

                                                                PHD student

                                                                ✉ Yuntao.Hao@med.uni-muenchen.de

                                                                ☎ 089- 4400- 57767

                                                                Room: D1.02


                                                                Johanna Ruf

                                                                PHD student

                                                                ✉ johanna.ruf@med.uni-muenchen.de

                                                                ☎ 089- 4400- 57707

                                                                Room: D1.02


                                                                Zorica Stijepic

                                                                Laboratory chemist

                                                                ✉ Zorica.Stijepic@med.uni-muenchen.de

                                                                ☎ 089- 4400- 54613

                                                                Room: D1.16


                                                                Stephanie Winterstetter

                                                                Chemical Technical Assistant (CTA)

                                                                ✉ StephanieKatrin.Winterstetter@med.uni-muenchen.de

                                                                Room: D1.02


                                                                Frances Strobl

                                                                Student Research Assistant

                                                                Room: D1.02



                                                                Michael Kammermeier

                                                                Student Research Assistant


                                                                Dr. Hans Demmelmair

                                                                Clinical Project Coordinator of the MS-Core Facility

                                                                ✉ hans.demmelmair@med.uni-muenchen.de

                                                                ☎ 089- 4400- 53692

                                                                Room: G1.16

                                                                Dr. Bernadeta Patro-Golab

                                                                Humboldt Research Fellow 

                                                                (Metabolomics Data Evaluation)

                                                                ✉ Bernadeta.Patrogolab@med.uni-muenchen.de



                                                                Luke Tu

                                                                PHD student

                                                                ✉ Luke.Tu@med.uni-muenchen.de

                                                                ☎ 089- 4400- 57767

                                                                Room: D1.02


                                                                Talat Bashir Ahmed

                                                                PHD student

                                                                ✉ T.Ahmed@med.uni-muenchen.de




                                                                Karin Kantke

                                                                Pharmaceutical Technical Assistant (PTA)

                                                                ✉



                                                                Andrea Vielhauer

                                                                Medical Technical Assistant (MTA)

                                                                ✉ Andrea.Vielhauer@med.uni-muenchen.de

                                                                ☎ 089- 4400- 53167

                                                                Room: D1.16


                                                                Irina Rupp

                                                                Student Research Assistant

                                                                Room: D1.02

                                                              • ChiFHA

                                                                Global e-Learning in Early Nutrition and Lifestyle for International Healthcare Professionals: Design and Evaluation of the Early Nutrition Specialist Programme (ENS), Brands, B., Tran, N. N., Baudendistel-Happ, E., Sanchez-Garcia, M., Fischer, M. R., & Koletzko, B. (2021). Nutrients, 13(3), 775. https://doi.org/10.3390/nu13030775

                                                                Early Nutrition eAcademy Southeast Asia e-Learning for Enhancing Knowledge on Nutrition during the First 1000 Days of Life, Brands B., Chomtho S., Suthutvoravut U., Chiong Meng Boey C., Tang, S. F., Godfrey, K. M., Koletzko, B., & For The ENeA Sea Project Group (2020). Nutrients, 12(6), 1817. https://doi.org/10.3390/nu12061817

                                                                Nutrition During Pregnancy, Lactation and Early Childhood and its Implications for Maternal and Long-Term Child Health: The Early Nutrition Project Recommendations, Koletzko, B., Godfrey, K. M., Poston, L., Szajewska, H., van Goudoever, J. B., de Waard, M., Brands, B., Grivell, R. M., Deussen, A. R., Dodd, J. M., Patro-Golab, B., Zalewski, B. M., & EarlyNutrition Project Systematic Review Group (2019). Annals of nutrition & metabolism, 74(2), 93–106. https://doi.org/10.1159/000496471

                                                                Long-Term Health Impact of Early Nutrition: The Power of Programming, Koletzko, B., Brands, B., Grote, V., Kirchberg, F. F., Prell, C., Rzehak, P., Uhl, O., Weber, M., & Early Nutrition Programming Project (2017). Annals of nutrition & metabolism, 70(3), 161–169. https://doi.org/10.1159/000477781

                                                                Curricula customization with the readerbench Framework, Gutu-Robu G., Trausan-Matu S., Dascalu M., Carabas M., Elisei A., Nistor N., Choi S., Spoerl R., & Koletzko B. (2018) Roceanu I., Beligan D., Ciolan L. & Stefan I. (eds.) In eLearning challenges and new horizons: Proceedings of the 14th International Scientific Conference "eLearning and Software for Education". National Defence University Publishing House. pp. 385-392. doi:10.12753/2066-026X-18-123

                                                                How growth due to infant nutrition influences obesity and later disease risk, Brands, B., Demmelmair, H., Koletzko, B., & EarlyNutrition Project (2014). Acta paediatrica (Oslo, Norway : 1992), 103(6), 578–585. https://doi.org/10.1111/apa.12593

                                                                Optimal nutrition in lactating women and its effect on later health of offspring: A systematic review of current evidence and recommendations (EarlyNutrition project), de Waard, M., Brands, B., Kouwenhoven, S. M. P., Lerma, J. C., Crespo-Escobar, P., Koletzko, B., Zalewski, B. M., & van Goudoever, J. B. (2017). Critical reviews in food science and nutrition, 57(18), 4003–4016. https://doi.org/10.1080/10408398.2016.1158149

                                                                Early nutrition programming of long-term health, Koletzko, B., Brands, B., Poston, L., Godfrey, K., Demmelmair, H., & Early Nutrition Project (2012). The Proceedings of the Nutrition Society, 71(3), 371–378. https://doi.org/10.1017/S0029665112000596

                                                                The Early Nutrition Programming Project (EARNEST): 5 y of successful multidisciplinary collaborative research, Koletzko, B., Brands, B., Demmelmair, H., & Early Nutrition Programming Project (2011). The American journal of clinical nutrition, 94(6 Suppl), 1749S–1753S. https://doi.org/10.3945/ajcn.110.000471

                                                                European Childhood Obesity Trial Study Group (2013). Early influences of nutrition on postnatal growth, Koletzko, B., Beyer, J., Brands, B., Demmelmair, H., Grote, V., Haile, G., Gruszfeld, D., Rzehak, P., Socha, P., Weber, M., & Nestle Nutrition Institute workshop series, 71, 11–27. https://doi.org/10.1159/000342533

                                                                The Power of Programming and the EarlyNutrition project: opportunities for health promotion by nutrition during the first thousand days of life and beyond, Koletzko, B., Brands, B., Chourdakis, M., Cramer, S., Grote, V., Hellmuth, C., Kirchberg, F., Prell, C., Rzehak, P., Uhl, O., & Weber, M. (2014). Annals of nutrition & metabolism, 64(3-4), 187–196. https://doi.org/10.1159/000365017

                                                                The effect of diet on the physical and mental development of children: views of parents and teachers in four European countries, Egan, B., Gage, H., Williams, P., Brands, B., Györei, E., López-Robles, J. C., Campoy, C., Decsi, T., Koletzko, B., & Raats, M. (2019). The British journal of nutrition, 122(s1), S31–S39. https://doi.org/10.1017/S000711451500032X

                                                                Frühkindliche Ernährung und späteres Adipositasrisiko. Hinweise auf frühe metabolische Programmierung [Infant feeding practice and later obesity risk. Indications for early metabolic programming], Koletzko, B., Schiess, S., Brands, B., Haile, G., Demmelmair, H., von Kries, R., & Grote, V. (2010). Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz, 53(7), 666–673. https://doi.org/10.1007/s00103-010-1079-y

                                                                Views of parents in four European countries about the effect of food on the mental performance of primary school children, Gage, H., Egan, B., Williams, P., Györei, E., Brands, B., López-Robles, J. C., Campoy, C., Koletzko, B., Decsi, T., & Raats, M. (2014). European journal of clinical nutrition, 68(1), 32–37. https://doi.org/10.1038/ejcn.2013.214

                                                                MS-Core Facility

                                                                Clinical Study

                                                                Complete list of published work of Prof. Berthold Koletzko

                                                              • ChiFHA
                                                                MS-Core Facility
                                                                • BiomarKID
                                                                • RisCoin (Covid immunization study),
                                                                • COVID-19 CORKUM (metabolomics and lipidomics study, steroidomics project)
                                                                • Childhood-Obesity Programme (CHOP, RCT with long term follow up)
                                                                Randomized trial in infants with long term follow-up; high protein supply promotes weight gain and obesity risk, mediated by higher amino acids, insulin and IGF-1 concentrations
                                                                • Toddler Milk Intervention Trial (TOMI, NCT02907502)

                                                                Effect of milk protein intake in young children on early growth and obesity risk

                                                                • NutriPROGRAM

                                                                Multi-omics approach using 1H-NMR and LC-MS metabolomics combined with epigenetic data sets of several cohort studies (CHOP, Generation-R, Candle, etc.) for epigenetic pathway analysis

                                                                • Thailand Breast Milk Project

                                                                Normalization of milk volume produced by the mother and intake by the infant, using [2H]-labelled water; analysis of serum, cord blood, milk, Fe and Zn

                                                                • Supplementation of breastfed LBWI in Indonesia

                                                                Pilot study completed, RCT ongoing

                                                                • ERC Advanced Grant Pathophysiology of Primary Aldosteronism (PAPA)
                                                                Clinical Study

                                                                • CHOP:

                                                                • GIRAFFE: Dairy Goat Co-operative (DGC), Hamilton, New Zealand - Sophie Gallier

                                                                • Hope: AAK BV Netherlands

                                                                • ToMI: Nestec Ltd., Ave, Nestlé 55 CH-1800 Vevey, Switzerland

                                                              • Koletzko Lab


                                                                AG Berthold Koletzko

                                                                Dr. von Hauner Children’s Hospital

                                                                Lindwurmstr. 4, D-80337 Munich

                                                                Email: office.koletzko@med.uni-muenchen.de


                                                                Subgroups Email address:

                                                                ChiFHA: kind.chifha@med.uni-muenchen.de

                                                                CHF: info@kindergesundheit.de




                                                              Research at CCRC Hauner

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                                                              Contact CCRC Hauner

                                                              Haunersches

                                                              CCRC Hauner

                                                              Kinderklinik und Kinderpoliklinik

                                                              im Dr. von Haunerschen Kinderspital

                                                              Ludwig Maximilians Universität München

                                                              Lindwurmstr. 4

                                                              80337 Munich, Germany

                                                              ☎ +49-89-4400-57705

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                                                              • Clinical research
                                                                • Interdisciplinary pediatric study center (Hauner iPSC)
                                                                • Ped-COVID-19 Study
                                                                • Michael Albert
                                                                • Scivias Study
                                                                • TRACE Study
                                                              • Research Labs
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                                                                • Braun Lab
                                                                • Feuchtinger Lab
                                                                • Griese Lab
                                                                • Hauck Lab
                                                                • Hübner Lab
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                                                                • Kim-Hellmuth Lab
                                                                • Klein Lab
                                                                • Kotlarz Lab
                                                                • Lange-Sperandio Lab
                                                                • von Mutius Lab
                                                                • Schaub Lab
                                                                • Schwerd Lab
                                                                • Schmid Lab
                                                                • Koletzko Lab
                                                              • PhD Program
                                                              • Technology platforms
                                                                • Bioinformatics
                                                                • Flow Cytometry
                                                                • High throughput sequencing
                                                                • Microscopy
                                                                • Pre-GMP Facility
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                                                                • Hauner Biobank
                                                              • News/Events
                                                                • Meinhard von Pfaundler-Lectures
                                                                • Klaus Betke Symposium
                                                              • Join us!